I don't think climate change will kill us off, I'm certain it will make life impossible for some, and incredibly difficult for most.

..until that giant asteroid impact, sure, why not?

Hell, even in the event of a giant asteroid hits and its total nuclear winter, there are too many of us, and too many of us with bomb shelters. The death toll might be billions, but people will live. We can filter our own air, and protect ourselves from radiation, what other species can do that?

We're about as extinction-proof as a species confined to a single planet is likely to be. It would take a near sterilization event to wipe out humanity given the resources we can now bring to bear. Still, surviving is a long way off from thriving.

Nothing is extinction proof.

Actually, I could be wrong. There are so many Humans, there'd always be plenty of survivors, depending on the event. Even a lot of bacteria (and other micro-organisms) could be classified as extinction proof.

A million years is practically forever in our personal experience. If we survive the next thousand years without a catastrophic setback, we will have likely sealed the deal.

Massive GRB from nearby neutron star can kill all of us before we can realize it.

Detection of GRB is very very very very very very very difficult (at-least from our current technological standpoint).

There are many ways humans can die similar way, massive volcanic activity, sucked by rough blackhole, super or hyper-nova in near by star etc.

Even there could be other unknown ways of dying : slowly degenerative DNA telomere or Y chromosome , or some quantum calamity

It would take a near sterilization event to wipe out humanity given the resources we can now bring to bear

A supernova in our neighborhood (closer than 100 light years) might do the trick. Not much we could do against that.

Or if we just happen to be aligned with the jet from a pulsar/quasar/black for any significant length of time.

A million years is practically forever in our personal experience. If we survive the next thousand years without a catastrophic setback, we will have likely sealed the deal.

Every extinct species had its next few thousand years.

I think we're extinction proof relative to MOST of what this planet can throw at us, however, as long as we're confined to this one chunk of rock (and for that matter, quadrant of space, really), all bets are off. There are too many things we can do to each other, and that the universe at large could throw at us, for us to be safe. Total nuclear war would kill off a good percentage of the species - I'm thinking upwards of 80% within the first 10 years from the primary attacks and subsequent food and resource shortages, followed by radiation-induced genetic defects that make re-population, short of some miracle mutation, unlikely. Also, any spacial (space-based) phenomenon strong enough to sterilize or completely destroy Earth would also most likely effect any other man made or modified habitat in the solar system, either directly, or indirectly through gravitational effect i.e.large black hole, huge asteroid, Planet-X[insert small snicker here] etc.

I think we have more to fear from the ideologues, capitalists, and academia promoting the GW AlGoreithm for population control, one world government, social justice, redistribution of wealth, tax incentives and research funding, then from the GW hoax. More people die from cold then from heat.

Atmospheric Carbon Dioxide was likely 18 times todays concentration during the Cambrian period when lifes diversity was at its greatest expansion.

I think we have more to fear from the ideologues, capitalists, and academia promoting the GW AlGoreithm for population control, one world government, social justice, redistribution of wealth, tax incentives and research funding, then from the GW hoax. More people die from cold then from heat. Atmospheric Carbon Dioxide was likely 18 times todays concentration during the Cambrian period when lifes diversity was at its greatest expansion.

Are we extinction proof? Only a religious nut could even come up with an idea like this.

As a species we do everything we can the opposite of what science tells us promotes species survival. Most notably isolated pockets and overpopulation. We are busily trying to put every person on the planet in a single intermingling group while increasing the population well beyond long term survival limits. We are suicidal as a group, like the proverbial Lemming.

Extinction probably isn't the right word. There are very, very few events that could wipe out humanity before we get a plan B set up in other parts of the Solar System or eventually on exo-planets. A large asteroid strike being one of them; getting flung out of the Solar System by a wandering neutron star or gas giant is another. But does anyone here really belive that humans will still be around in their current form in, say, a million years?