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Genetics
Retrospective genomic characterization of the 2020 Ebola outbreak
Epidemiology researchers are harnessing tools developed by the Johns Hopkins Applied Physics Laboratory (APL) in Laurel, Maryland, to untangle the origins of the 2020 Ebola virus disease outbreak in the Democratic Republic ...
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Genetics
Researchers discover dynamic DNA structures that regulate the formation of memory
An international collaborative research team, including scientists from UQ's Queensland Brain Institute (QBI), has discovered a novel mechanism underlying memory involving rapid changes in a specific DNA structure.
22 minutes ago
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Medical research news
Potential modifier gene identified as cause of ciliary pathology in retinitis pigmentosa patient
Ciliopathies are rare diseases in which the formation or function of cilia, cylindrical-shaped extensions found on the surface of many cells, is altered. There is a high degree of ciliary specialization, ranging from motile ...
22 minutes ago
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How myeloid cell replacement could help treat autoimmune encephalomyelitis
Autoimmune conditions such as multiple sclerosis (MS) are disorders of the immune system associated in this case with demyelination of the central nervous system (CNS). The term demyelination describes damage to the layer ...
Dietary treatment found to be more effective than medicines in irritable bowel syndrome
A study conducted at the University of Gothenburg found that with dietary adjustments, more than 7 out of 10 irritable bowel syndrome (IBS) patients had significantly reduced symptoms, compared with medications. The work ...
3 hours ago
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Using AI to trace the origins of metastatic cancer cells
A large team of cancer researchers affiliated with several institutions in China, working with a pair of colleagues in the U.S., has found that artificial intelligence applications can be used to trace the origins of metastatic ...
Geneticists develop world's first bioinformatic tool to identify amyloids consisting of multiple copies of same protein
Scientists from St Petersburg University and the University of Montpellier have developed the first software enabling the prediction of pairs of proteins in amyloid fibrils capable of co-aggregation, i.e. a process by which ...
2 hours ago
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Engineered peptides open new avenue for immunotherapy drug development
In a new study published in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cancer Center have designed a new method for developing immunotherapy drugs using engineered peptides to elicit ...
6 hours ago
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Signs of multiple sclerosis show up in blood years before symptoms, study finds
In a discovery that could hasten treatment for patients with multiple sclerosis (MS), UC San Francisco scientists have discovered a harbinger in the blood of some people who later went on to develop the disease.
6 hours ago
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Study of cancer-induced liver inflammation finds a promising therapeutic target
Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy. Now, a team led by researchers ...
6 hours ago
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Immune cells carry a long-lasting 'memory' of early-life pain
In recent years, a growing body of research has shown that the human body can "remember" the pain of newborn injuries—including life-saving surgeries—all the way into adolescence.
19 hours ago
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A common pathway in the brain that enables addictive drugs to hijack natural reward processing identified
Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems. Published online ...
21 hours ago
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Study finds that human neuron signals flow in one direction
Contrary to previous assumptions, nerve cells in the human neocortex are wired differently than in mice. Those are the findings of a new study conducted by Charité-Universitätsmedizin Berlin and published in the journal ...
21 hours ago
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Scientists identify airway cells that sense aspirated water and acid reflux
When a mouthful of water goes down the wrong pipe—heading toward a healthy person's lungs instead of their gut—they start coughing uncontrollably. That's because their upper airway senses the water and quickly signals ...
21 hours ago
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Environment may influence metacognitive abilities more than genetics
Twin studies have proven invaluable for teasing out the effects of both genetics and the environment on human biology. In a study published April 2 in Cell Reports, researchers studied pairs of twins to look at how the interplay ...
22 hours ago
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DNA vaccine against Zika performs well in tests on mice
In Brazil, researchers at the University of São Paulo (USP) and the Pernambuco division of Oswaldo Cruz Foundation (FIOCRUZ) are developing a Zika vaccine. The formulation was tested on mice and found to be efficacious, ...
23 hours ago
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Mutations in noncoding DNA become functional in some cancer-driving genes
Some genes are known to drive cancer, and astonishing new research shows why: Mutations in the noncoding regions become functional, altering the abundance of messenger RNA, or mRNA, and potentially facilitating cell proliferation. ...
22 hours ago
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Novel cell therapy treatments offer promise to immune-compromised children
In a first-of-its-kind clinical trial, researchers found that intravenous therapies made from virus-specific T-cells (VST) can effectively treat immunocompromised pediatric patients, far surpassing the current standard of ...
22 hours ago
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COVID-19 booster immunity lasts much longer than primary series alone, study shows
Thinking about getting a spring-time booster shot? A new study coming out of York University's Centre for Disease Modelling in the Faculty of Science shows that immunity after a COVID-19 booster lasts much longer than the ...
20 hours ago
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Researchers discover new therapeutic target for non-small cell lung cancer
Non-small cell lung cancer accounts for nearly 85% of all lung cancer cases. Targeted immunotherapy is a common treatment, but it does not work for everyone. However, a new Moffitt Cancer Center study published in the journal ...
19 hours ago
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