[Home]   [Full version]  

Scientists lose hope over AIDS vaccine

Apr 25 ,Medicine & Health


A survey of leading U.S. and British AIDS researchers said many scientists see little hope of an effective vaccine against HIV in the near future.

Just two of the 35 scientists surveyed said they were more optimistic about the prospects for an HIV vaccine than they were a year ago, while only four said they were more optimistic now than they were five years ago, the survey by Britain's Independent newspaper said.

The survey found that nearly two-thirds believed an HIV vaccine will not be developed within the next 10 years. Some of the scientists said it may take at least 20 more years of research.

Researchers said the direction of AIDS research needs to change after the failure last year of a promising prototype vaccine used as an animal model for more than a decade. AIDS researcher Robert Gallo told the newspaper the vaccine's failure is similar to the Challenger disaster that forced the space agency to ground its space shuttle fleet for years.

Copyright 2008 by United Press International

Related stories:

3 share Nobel prize for work on AIDS and cancer
(AP) -- Three European scientists shared the 2008 Nobel Prize in medicine on Monday for separate discoveries of viruses that cause AIDS and cervical cancer, breakthroughs that helped doctors fight the deadly diseases.
A DNA-based vaccine shows promise against avian flu
(PhysOrg.com) -- Though it has fallen from the headlines, a global pandemic caused by bird flu still has the United States’ Centers for Disease Control and Prevention on high alert. Yet, to date, the only vaccines that have proven even semi-effective are produced in chicken eggs, take five to six months to prepare and act against a single variant of the H5N1 virus, which mutates incredibly quickly. Now, new research by scientists in New York and Taiwan has led to a vaccine with the potential to stop most strains of H5N1 flu viruses in their tracks.
NTDs burden in Latin America and the Caribbean may exceed that of HIV/AIDS, TB and malaria
According to a new analysis published September 24th in the open-access journal PLoS Neglected Tropical Diseases, "The Neglected Tropical Diseases of Latin America and the Caribbean: A Review of Disease Burden and Distribution and a Roadmap for Control And Elimination,", neglected tropical diseases (NTDs) as a group may have surpassed HIV/AIDS, tuberculosis and malaria as the most prevalent infectious diseases in Latin America and the Caribbean. The analysis found that NTDs are the most common infections of approximately 200 million of the poorest people in the region. They include tens of millions of cases of intestinal worm infections, and almost 10 million cases of Chagas disease, as well as schistosomiasis, trachoma, dengue fever, leishmaniasis, lymphatic filariasis (LF), and onchocerciasis.
Behavioral intervention works to reduce risky behavior
In an effort to curb the rising rates of HIV and sexually transmitted infections (STIs) along the Mexico-US border, a binational team of researchers led by the University of California, San Diego School of Medicine have shown that brief but personalized behavioral counseling significantly reduced rates and improved condom use among female sex workers in Tijuana and Ciudad Juarez, Mexico.
Why some primates, but not humans, can live with immunodeficiency viruses and not progress to AIDS
Key differences in immune system signaling and the production of specific immune regulatory molecules may explain why some primates are able to live with an immunodeficiency virus infection without progressing to AIDS-like illness, unlike other primate species, including rhesus macaques and humans, that succumb to disease.
Personalized immunotherapy to fight HIV/AIDS
For a long time, the main obstacle to creating an AIDS vaccine has been the high genetic variability of the HIV virus. Dr. Jean-Pierre Routy and his team from the Research Institute of the McGill University Health Centre (MUHC), in collaboration with Dr. Rafick Sékaly from the Université de Montréal, have overcome this difficulty by designing a personalized immunotherapy for HIV-infected patients. The team's findings were presented on August 5 at the XVII International AIDS Conference in Mexico City.
Trapping white blood cells proves novel strategy against chronic viral infections
Seeing disease-fighting white blood cells vanish from the blood usually signals a weakened immune system. But preventing white blood cells' circulation by trapping them in the lymph nodes can help mice get rid of a chronic viral infection, researchers at Yerkes National Primate Research Center and the Emory Vaccine Center have found.
Rare case explains why some infected with HIV remain symptom free without antiretroviral drugs
AIDS experts at Johns Hopkins say they have compelling evidence that some people with HIV who for years and even decades show extremely low levels of the virus in their blood never progress to full-blown AIDS and remain symptom free even without treatment, probably do so because of the strength of their immune systems, not any defects in the strain of HIV that infected them in the first place.

News discussion:

Medicine & Health news

[Home]   [Full version]