[Home]   [Full version]  

Treatment of asthma: Stepping up treatment and also stepping it down

Apr 09 ,Medicine & Health


Asthma symptoms vary greatly among individuals and vary at times with each individual. In this comprehensive study in the April issue of Mayo Clinic Proceedings, researchers address the prevalence and process of step-down therapy as symptoms subside. Of the 397 adults and children studied, 64 percent had at least one change in medication dose during the two years of the study. Most changes were step-up in doses during an asthma flare. Step-down changes were far less common.

Lead author Barbara Yawn., M.D., from the Department of Research at Olmsted Medical Center in Rochester, Minn., comments that “patients indicate it is important to them to take the lowest possible dose of medication to maintain asthma control, suggesting we need to step down therapy when feasible.”

This is one of the first studies to address the frequency, type and context of step-up and step-down changes in asthma therapy for children and young adults. The study asserts that asthma care continues to be episodic, with most physician visits occurring at a flare-up. Additional research will help determine the best course of long-term treatment for patients with asthma.

Source: Mayo Clinic

Related stories:

Exercise effective in helping pregnant women kick the habit
Exercise could be a useful tool in helping pregnant women to give up smoking, according to new research published today in the open access journal BMC Public Health. Despite the warnings, 17% of women in the UK and 20% of women in the US still admit to smoking during pregnancy. This often leads to lower birth weight, higher infant mortality, and is linked to learning difficulties, problem behaviour and asthma in childhood.
Exhaled nitric oxide monitoring does not improve on guidelines-based asthma management
Exhaled nitric oxide serves as a biomarker of inflammation in the lungs, and proponents have suggested that monitoring nitric oxide levels could help improve management of asthma. However, new research, which will be published in the Sept. 20 issue of The Lancet, indicates that adolescent and young adult patients whose asthma is managed according to the latest NIH guidelines do not benefit from the addition of nitric-oxide monitoring.
Heavy breathing -- an obscure link in asthma and obesity
There is a strong link between obesity and asthma and as the prevalence of both conditions has been increasing steadily, epidemiologists have speculated that there is an underlying condition that connects the two. But one long-suspected link, the systemic inflammation associated with obesity, has been ruled out by a recent New Zealand study that found no evidence of its involvement.
Asthma monitoring on the Web
An inexpensive web-enabled device for measuring lung function in patients with asthma and other disorders is being developed by researchers at Texas Instruments, in Bangalore, India, and co-workers. Writing in the International Journal of Biomedical Engineering and Technology, the team explains how the devise could allow physicians to monitor their patients remotely and quickly instigate medical attention in an emergency.
Back-to-School Means Beware of Asthma for Some
(PhysOrg.com) -- Asthma is a leading cause of death and disability in children younger than 18 years old, and is one of the leading causes of hospitalization in school-age children. Since children spend up to 30 percent of their day in school, a University of Missouri respiratory therapy expert says it is imperative that every school employee, from teachers to bus drivers, understand the condition and how to treat it.
When our protective armor shows weakness
New knowledge points to the fact that a genetically induced lack of filaggrin, a key protein of the skin barrier, plays a decisive role in the origin of allergies. In a large study on more than 3000 school-children scientists of the Helmholtz Zentrum München and the Technische Universität München found that about 8% of the German population carry variations of the filaggrin gene, which raise the risk to develop atopic dermatitis more than threefold. In addition, these genetic variations predispose to hay fever and asthma in those with atopic dermatitis.
Lung inflammation from influenza could be turned off with new discovery
A new discovery could lead to treatments which turn off the inflammation in the lungs caused by influenza and other infections, according to a study published today in the journal Nature Immunology.
Out-of-pocket health care costs for disabled children vary widely by state
The size of the financial burden on families with disabled children largely depends on which state they live in, according to a new study conducted by the schools of social work at the University of North Carolina at Chapel Hill and Washington University in St. Louis, Mo.

News discussion:

Medicine & Health news

[Home]   [Full version]