[Home]   [Full version]  

Viruses may play a role in lung cancer development

Apr 25 ,Medicine & Health


Papers presented at the 1st European Lung Cancer Conference, jointly organized by the European Society for Medical Oncology (ESMO) and the International Association for the Study of Lung Cancer (IASLC) in Geneva, Switzerland highlight emerging evidence that common viruses may contribute to the development of lung cancer.

Experts agree that smoking is by far the most important factor that contributes to lung cancer development. But other factors can play a role in some cases.

In one report at the conference Dr. Arash Rezazadeh and colleagues from the University of Louisville, Kentucky, USA, describe the results of a study on 23 lung cancer samples from patients in Kentucky.

The researchers found six samples that tested positive for the presence of human papilloma virus (HPV), the virus that also causes many cases of cervical cancer. One was later shown to be a cervical cancer that had spread to the lungs.

Of the remaining 5 virus-positive samples, two were HPV type 16, two were HPV type 11 and one was HPV type 22. "The fact that five out of 22 non-small-cell lung cancer samples were HPV-positive supports the assumption that HPV contributes to the development of non-small-cell lung cancer," the authors say.

All the patients in this study were also smokers, Dr. Rezazadeh notes. "We think HPV has a role as a co-carcinogen which increases the risk of cancer in a smoking population," he says.

In another paper (Abstract No. 125PD; Friday 25th April, 09:50), Israeli researchers suggest that measles virus may also be a factor in some lung cancers. Their study included 65 patients with non-small-cell lung cancer, of whom more than half had evidence of measles virus in tissue samples taken from their cancer.

"Measles virus is a ubiquitous human virus that may be involved in the pathogenesis of lung cancer," says lead author Prof. Samuel Ariad from Soroka Medical Center in Beer Sheva, Israel. "Most likely, it acts in modifying the effect of other carcinogens and not as a causative factor by itself."

Source: European Society for Medical Oncology

Related stories:

Poll finds women can do more to prevent cancer... but aren't
When it comes to preventing cancer, women believe they're doing more than they actually are. Perhaps most surprising, women are more afraid of getting Alzheimer's disease than cancer, even though cancer causes nearly ten times more deaths per year.
Eat well, get fit, stop smoking — prevent cancer
If you wanted to start today to reduce your chances of getting cancer, what would you have to do? Lose excess weight, get more exercise, eat a healthy diet and quit smoking.
Peptide targets latent papilloma virus infections
While a newly marketed vaccine promises to drastically reduce human papilloma virus (HPV) infections, the major cause of cervical cancer, a new discovery by University of California, Berkeley, researchers could some day help the millions of people already infected and at constant risk of genital warts and cancer.
Anti-cancer drug prevents, reverses cardiovascular damage in mouse model of premature aging disorder
An experimental anti-cancer drug can prevent -- and even reverse -- potentially fatal cardiovascular damage in a mouse model of progeria, a rare genetic disorder that causes the most dramatic form of human premature aging, National Institutes of Health (NIH) researchers reported today.
Red wine decreases the risk of lung cancer
Moderate consumption of red wine may decrease the risk of lung cancer in men, according to a report in the October issue of Cancer Epidemiology, Biomarkers & Prevention¸ a journal of the American Association for Cancer Research.
3 share Nobel prize for work on AIDS and cancer
(AP) -- Three European scientists shared the 2008 Nobel Prize in medicine on Monday for separate discoveries of viruses that cause AIDS and cervical cancer, breakthroughs that helped doctors fight the deadly diseases.
Smoking and solid fuel use in homes in China projected to cause millions of deaths
If current levels of smoking and biomass and coal fuel use in homes continues, between 2003 and 2033 there will be an estimated 65 million deaths from chronic obstructive pulmonary disease (COPD) and 18 million deaths from lung cancer in China, accounting for 19% and 5% of all deaths in that country during this period.
Probing Question: Could your kitchen counters be radioactive?
Verde Butterfly. Black Galaxy. Kashmir Gold. If you’ve remodeled your kitchen in the last decade, chances are you encountered one of the 1,600 varieties of granite imported into the United States from 64 different countries. According to recent market research, demand for natural stone countertops has increased 5 percent annually between 2001 and 2006, with granite being the most popular option. And why not? Granite is not only durable, resistant to mold and mildew, and easy to clean, but because no two pieces of granite are alike, your counter will have its own unique look.

News discussion:

Medicine & Health news

[Home]   [Full version]