[Home]   [Full version]  

Italians report stem-cell advances

Sep 06 ,General Science


Italian scientists have reportedly made important advances in stem-cell research, specifically for kidney and liver disease.

The researchers say the cells appear able to turn into an array of other body cells, the Italian news agency ANSA reported. The scientists said their findings were made in adults, not using embryonic stem cells.

A Florence team led by immunologist Sergio Romagnani reported identifying kidney stem cells that can help damaged kidneys repair themselves.

Romagnani told a news conference the cells can be cultivated in the lab so as to "multi-differentiate" into other types of cells: bone cells, adipose cells and even nerve cells, offering the hope of reversing degenerative diseases that also affect kidneys, ANSA said.

The research appears in the Journal of the American Society of Nephrology.

Scientists in Turin announced a similar discovery involving adult stem cells in livers.

"The progenitor cells identified by our team are able to differentiate into liver cells, bone cells, blood cells and even pancreatic cells that produce insulin," lead researcher Benedetta Bussolati said.

The Turin study is detailed in the journal Stem Cells.

Copyright 2006 by United Press International

Related stories:

Resetting immune system in bid to beat scleroderma
(AP) -- First Bari Martz's fingers turned blue. Then she started gasping for breath, and her joints stiffened so that she couldn't even open her hands. Doctors diagnosed scleroderma, part of an insidious family of diseases where the immune system attacks a patient's own body, sometimes enough to kill.
Cartilage regeneration '20,000 Leagues Under the Sea'
Bioengineers at Rice University have discovered that intense pressure -- similar to what someone would experience more than a half-mile beneath the ocean's surface -- stimulates cartilage cells to grow new tissue with nearly all of the properties of natural cartilage. The new method, which requires no stem cells, may eventually provide relief for thousands of arthritis sufferers.
Nanotechnology offers hope for treating spinal cord injuries, diabetes, and Parkinson's disease
Imagine a world where damaged organs in your body—kidneys, liver, heart—can be stimulated to heal themselves. Envision people tragically paralyzed whose injured spinal cords can be repaired. Think about individuals suffering from the debilitating effects of Parkinson’s or Alzheimer’s relieved of their symptoms – completely and permanently.
2-protein team would be lost without each other
Just as a hard-charging person sometimes needs a calming partner to be more effective, so it is with a pair of critical proteins that promote cell division and growth in the rapidly expanding root tip of plants.
50 atoms thick membrane sorts individual molecules
A newly designed porous membrane, so thin it's invisible edge-on, may revolutionize the way doctors and scientists manipulate objects as small as a molecule.
Key gene in kidney development found
U.S. scientists in Memphis, Tenn., say they've found that a gene called Six2 plays a critical role in the development of human kidneys.
Mayo researchers explore issues related to multiple myeloma treatment
Multiple myeloma (MM) is a cancer of plasma cells that affects approximately 3 in 100,000 people each year. Although there is no cure for this disease, researchers have developed treatments that help relieve pain, control complications, and slow the progress of MM in many patients. Unfortunately, some of the most effective therapies also have toxic side effects that can pose serious health risks and reduce quality of life. In the October issue of Mayo Clinic Proceedings, two articles authored by Mayo researchers address the issue of how to balance the risks and benefits associated with MM treatments.
Scientists identify a molecule that coordinates the movement of cells
Even cells commute. To get from their birthplace to their work site, they sequentially attach to and detach from an elaborate track of exceptionally strong proteins known as the extracellular matrix. Now, in research to appear in the October 3 issue of Cell, scientists at the Howard Hughes Medical Institute and Rockefeller University show that a molecule, called ACF7, helps regulate and power this movement from the inside - findings that could have implications for understanding how cancer cells metastasize.

News discussion:

General Science news

[Home]   [Full version]