[Home]   [Full version]  

Mammography facility characteristics associated with accuracy of screening

Jun 10 ,Medicine & Health


Some characteristics of mammography facilities are associated with the accuracy of interpretation of screening mammograms, according to a study published online June 10 in the Journal of the National Cancer Institute.

Previous studies have suggested that patient characteristics, such as age, are associated with variations in the accuracy of screening mammograms. Similarly, characteristics of the radiologist who interprets the mammograms, such as his or her reading experience, are associated with variations in accuracy. The impact of the type of facility or its characteristics on mammogram accuracy was unknown, but the information could help identify better practices and better places to obtain a mammogram.

In the current observational study, Stephen Taplin, M.D., of the National Cancer Institute in Bethesda, Md., and colleagues surveyed 53 mammography facilities between 1992 and 2002 to look for associations between facility characteristics and interpretive accuracy. The researchers were able to analyze data from 44 facilities, which altogether performed 484,463 screening mammograms on 237,669 women. Of those, 2,686 women were diagnosed with breast cancer.

On average, the facilities identified cancer when it was present (sensitivity) in 79.6 percent of breast cancer cases that occurred within one year and correctly categorized a mammogram as cancer-free (specificity) 90.2 percent of the time. The likelihood of cancer in women who were referred for additional imaging or evaluation due to an abnormal mammogram was 4.1 percent. On average, 38.8 percent of the women referred for a biopsy from each facility were found to have cancer. The likelihood of cancer among the women with any additional evaluation, or those referred for biopsy, varied substantially between facilities. The likelihood that a mammogram was accurately read as cancer-free varied by facility but the likelihood that a cancer was identified when it was present did not.

Several facility characteristics were associated with a higher measure of accuracy that combines sensitivity and specificity, including those that offered screening mammograms alone versus those that offered diagnostic and screening mammograms, and those that had a breast imaging specialist reading the mammograms versus those that did not.

If these associations are validated in future prospective studies, the information could help both patients and mammography facilities. "Understanding how facility characteristics influence interpretive accuracy is important because it could allow women and physicians to choose a mammography facility based on characteristics that are more likely to be associated with higher quality. Radiologists could also change the facilities' structures or processes to include practices that improve interpretive accuracy," the authors write.

Source: Journal of the National Cancer Institute

Related stories:

New model predicts whether patients will be free of renal cancer 12 years after initial treatment
A UT Southwestern Medical Center physician and other researchers have developed a unique statistical model that predicts the probability of a patient being cancer free 12 years after initial surgical treatment.
Salivary diagnostics, the 'magic mirror' to your health ... at your personal computer
Accuracy, convenience, and non-invasiveness are the most critical characteristics for any diagnostic tool. A new concept, Salivaomics Knowledge Base (SKB), an in silico (i.e., performed on computer or via computer simulation) saliva diagnostic atlas, is launching today during the 37th Annual Meeting of the American Association for Dental Research in Dallas, Texas.
Digital mammography superior to film mammography in some cases
For some women, digital mammography may be a better screening option than film mammography, according to newly published results from the Digital Mammographic Imaging Screening Trial (DMIST). The results appear in the February issue of Radiology. The study found that digital mammography performed better than film mammography for pre- and perimenopausal women under age 50 with dense breasts.
Nanotech researchers discover cancer cells 'feel' much softer than normal cells
A multidisciplinary team of UCLA scientists were able to differentiate metastatic cancer cells from normal cells in patient samples using leading-edge nanotechnology that measures the softness of the cells.
Breakthrough In AFM Opens New Avenues Of Research in Nanoscience
Molecular Imaging is an Research and Development 100 Awards winner for its new PicoTREC. The awards are sponsored by Research and Development Magazine and recognize the top 100 products introduced into the marketplace during the year. PicoTREC is the only commercially available instrument to add real-time, simultaneous Topography and RECognition imaging capability to the atomic force microscope (AFM). A breakthrough tool for AFM, PicoTREC allows researchers to pursue new avenues of discovery in all areas of nanotechnology and nanoscience.
Cells that Avoid Suicide May Become Cancerous
(PhysOrg.com) -- When a cell's chromosomes lose their ends, the cell usually kills itself to stem the genetic damage. But University of Utah biologists discovered how those cells can evade suicide and start down the path to cancer.
MU researcher finds new method to create cancer drugs
When fixing a car, it's a good idea to have more than one type of wrench. Similarly, when doctors treat cancer patients, they like to have different "tools" available. Cancer tumors can be big or small. Some tumors grow very fast, while others grow slowly. Now, a University of Missouri researcher has developed a method that would make it easier for doctors to pick and choose different radiopharmaceuticals to treat different types and sizes of cancer and tumors.
Young women w/ early form of breast cancer no more likely to experience recurrence than older women
Young women with DCIS, a common form of early breast cancer that arises in and is confined to the mammary ducts, are presumed more likely to have recurrences than older women with the same diagnosis. But a new study from Fox Chase Cancer Center rebuffs this conventional thinking.

News discussion:

Medicine & Health news

[Home]   [Full version]