Moderate exercise cuts rate of metabolic syndrome

Research from Duke University Medical Center shows that even a modest amount of brisk walking weekly is enough to trim waistlines and cut the risk of metabolic syndrome (MetS), an increasingly frequent condition linked to obesity and a sedentary lifestyle.

It’s estimated that about a quarter of all U.S. adults have MetS, a cluster of risk factors associated with greater likelihood of developing heart disease, diabetes and stroke: large waist circumference, high blood pressure, high levels of triglycerides, low amounts of HDL, or “good” cholesterol, and high blood sugar. To be diagnosed with MetS, patients must have at least three of these five risk factors, and according to many studies, a growing number of people do.

But Johanna Johnson, a clinical researcher at Duke Medical Center and the lead author of a new study examining the impact of exercise on MetS, said a person can lower risk of MetS by walking just 30 minutes a day, six days per week. “That’s about 11 miles per week. And our study shows that you’ll benefit even if you don’t make any dietary changes.”

“The results of our study underscore what we have known for a long time,” said Duke cardiologist William Kraus. “Some exercise is better than none; more exercise is generally better than less, and no exercise can be disastrous.”

The study appears in the December 15 issue of the American Journal of Cardiology.

The results come from a multi-year, federally funded study called STRRIDE (Studies of a Targeted Risk Reduction Intervention through Defined Exercise) that examined the effects of varying amounts and intensity of exercise on 171 middle-aged, overweight men and women.

Before exercising regularly, 41 percent of the participants met the criteria for MetS. At the end of the 8-month exercise program, only 27 percent did.

“That’s a significant decline in prevalence,” said Johnson. “It’s also encouraging news for sedentary, middle-aged adults who want to improve their health. It means they don’t have to go out running four or five days a week; they can get significant health benefits by simply walking around the neighborhood after dinner every night.”

Still, some exercise regimens were better than others. Those who exercised the least, walking about 11 miles per week, gained significant benefit, while those who exercised the most, jogging about 17 miles per week, gained slightly more benefit in terms of lowered MetS scores.

One group puzzled the researchers, however. Those who did a short period of very vigorous exercise didn't improve their MetS scores as much as those who performed less intense exercise a longer period.

Kraus said there may be more value in doing moderate intensity exercise every day rather than more intense activity just a few days a week.

In all three of the study's exercise groups, waistlines got smaller over the 8-month period. In general, men who exercised saw greater improvement in their MetS risk factors than women. But Johnson points out that at baseline, the men generally had worse scores than women, “so they had more room to improve,” she said.

Over the course of the STRRIDE study, the inactive control group – those who didn’t change their diet or activity level at all – gained an average of about one pound and a half-inch around the waist. “That may not sound like much, but that’s just six months," Kraus said. "Over a decade, that’s an additional 20 pounds and 10 inches at the beltline.”

Source: Duke University Medical Center

Related stories:

Daily exercise dramatically lowers men's death rates
Increased exercise capacity reduces the risk of death in African-American and Caucasian men, researchers reported in Circulation: Journal of the American Heart Association.
At risk for peripheral arterial disease? Simple quiz provides key so you can circulate better
Ten million Americans have peripheral arterial disease (PAD), and research shows that the highest risk populations include African-Americans (twice as likely to develop clogged leg arteries), seniors (12-20 percent develop PAD) and diabetics (one in three who are over the age of 50 develop PAD). Legs for Life®—a community health and public information program—recommends that older Americans take its free, online self-assessment quiz.
Loneliness undermines health as well as mental well-being
Feeling connected to others is vital to a person's mental well-being, as well as physical health, research at the University of Chicago shows.
1 in 2 adults at risk for painful knee arthritis
A landmark government study suggests nearly one in two people (46%) will develop painful knee osteoarthritis over their lifetime, with the highest risk among those who are obese. According to the Arthritis Foundation, the study underscores the immediate need for the public to understand what they can do to reduce the tremendous pain, disability and cost associated with arthritis.
Substance found in fruits and vegetables reduces likelihood of the flu
Mice given quercetin, a naturally occurring substance found in fruits and vegetables, were less likely to contract the flu, according to a study published by The American Physiological Society. The study also found that stressful exercise increased the susceptibility of mice to the flu, but quercetin canceled out that negative effect.
Babies' rapid weight gain linked to higher blood pressure as adults
The pace of weight gain in early childhood may be associated with increased blood pressure in adulthood, according to a report in Hypertension: Journal of the American Heart Association.
Survey: 'Tanorexia' common among university students
A new study conducted at a large university finds more than 25 percent of those surveyed reported symptoms of tanning dependence, including symptoms similar to alcohol and drug-addicted individuals. Suggestively, the study also found those with a tanning dependence tend to be more likely to be thin and smoke cigarettes than others. The study by researchers at Fox Chase Cancer Center is published in the September/October issue of the American Journal of Health Behavior.
Pfizer resuming ads for Lipitor after controversy
(AP) -- Television ads for the world's top-selling drug, cholesterol fighter Lipitor, are back, six months after Pfizer Inc. pulled them amid charges its use of a celebrity doctor endorser who's never practiced medicine misled the public. This time, Pfizer is leaving out the celebrity.

News discussion:

Medicine & Health news