"Random DNA" is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular ...
Evolution
Mar 6, 2024
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13
Researchers can engineer cells to express new genes and produce specific proteins, giving the cells new parts to work with. But, it's much harder to provide cells with instructions on how to organize and use those new parts. ...
Cell & Microbiology
Feb 15, 2024
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60
Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a ...
Biotechnology
Jan 2, 2024
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155
Researchers at Nanjing Normal University, China, have investigated the genetic underpinnings of mammalian longevity in search of new strategies to extend human lifespan.
Researchers have proposed a new model for the evolution of higher brain functions and behaviors in the Hymenoptera order of insects. The team compared the Kenyon cells, a type of neuronal cell, in the mushroom bodies (a part ...
Plants & Animals
May 5, 2023
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666
Professor Hirohide Saito and his research team have developed a new approach to control mRNA translation using Cas proteins, thus expanding the variety of mRNA switches and making it easier to build synthetic gene circuits ...
Biotechnology
Apr 24, 2023
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56
Mammalian cells are inherently complex due to subcellular compartments, thereby making the process of robust transcript targeting of nucleic acids somewhat challenging in the molecular biology lab. In a recent report now ...
Rice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated.
Biochemistry
Feb 14, 2023
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36
New research at the University of Chicago has found that the same machinery used by mammalian cells to drive cellular differentiation also plays a critical role in activating genes in yeast in response to environmental stress.
Cell & Microbiology
Nov 22, 2022
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68
Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Biotechnology
Nov 1, 2022
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28
