New method advances single-cell transcriptomic technologies

Single-cell transcriptomic methods allow scientists to study thousands of individual cells from living organisms, one-by-one, and sequence each cell's genetic material. Genes are activated differently in each cell type, giving ...

How the environment and the microbiome jointly shape the body

All multicellular living beings are colonized by an unimaginably large number of microorganisms and have developed together with them from the very beginning of multicellular life. The natural microbiome, i.e. the totality ...

Pinpointing the molecular mechanisms of ageing

Although each and every one of us goes through it, ageing is a poorly understood process. Researchers have used a biomarker called the epigenetic clock to identify a gene that is closely linked to ageing in humans. The study, ...

Cell polarity: An aurora over the pole

Even before the fertilised egg or zygote can start dividing into daughter cells that form the future tissues and organs during the development of a multicellular organism, the symmetrical zygote needs to become asymmetrical ...

New machine learning model describes dynamics of cell development

From their birth through to their death, cells lead an eventful existence. Thanks to single-cell genomics, their destiny in large cell populations can now be analyzed. However, this method destroys the cell, which makes it ...

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