Scientists unveil the functional landscape of essential genes

A team of scientists at Whitehead Institute and the Broad Institute of MIT and Harvard have systematically evaluated the functions of more than 5,000 essential human genes using a novel, pooled, imaged-based screening method. ...

Exploring molecular boundaries in DNA

It's important to be well organized. And this is especially true for the genome—the entirety of an organism's genetic information, also known as DNA. The genomic DNA is several meters long but has to fit inside the cell's ...

Crystal study may resolve DNA mystery

When cells reproduce, the internal mechanisms that copy DNA get it right nearly every time. Rice University bioscientists have uncovered a tiny detail that helps understand how the process could go wrong.

The fungal effector Rip 1 suppresses maize host defense responses

Plant colonization by biotrophic pathogens requires sophisticated strategies for tissue invasion, defense suppression and metabolic manipulation to loot nutrients necessary for their growth and reproduction. The biotrophic ...

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